“Adam Kucharski, mathematical modeller and Professor of Infectious Disease Epidemiology at the London School of Hygiene & Tropical Medicine in London, UK, was one of the most reliable expert sources for many reporters wrestling with the scientific debates and dilemmas [around COVID-19]. He has now distilled his experience from working on both the pandemic and the epidemiology of other disease outbreaks, such as Zika virus disease and Ebola virus disease, into Proof: The Uncertain Science of Certainty, an exceptionally clear and engaging account of how scientists demonstrate truth and falsity. By showing that the matter often requires us to accept uncertainty … Read More
“[Abstract] At least 60% of stroke, 40% of dementia and 35% of late-life depression (LLD) are attributable to modifiable risk factors, with great overlap due to shared pathophysiology. [..] Identified risk factors included alcohol (normalised β-coefficient highest category: −34), blood pressure (130), body mass index (70), fasting plasma glucose (94), total cholesterol (22), leisure time cognitive activity (−91), depressive symptoms (57), diet (51), hearing loss (60), kidney function (101), pain (42), physical activity (−56), purpose in life (−50), sleep (76), smoking (91), social engagement (53) and stress (55). [article’s Discussion section] When assessing individual components, hypertension emerged as the factor … Read More
The Trump administration is manipulating government-sponsored research to get the answers it wants. “Since its first days, the new Trump administration has clearly shown where it thinks scientific attention should not be focused: It has attempted to censor federal scientific data, cut billions in government spending on research, and compromised care for some of the world’s most at-risk populations. Now, as the nation’s leaders have begun to encourage inquiry into specific areas, they are signaling that they’re willing to not just slash and burn research that challenges their political ideology but to replace it with shoddy studies designed to support … Read More
Hearing aids and cochlear implants have been getting better for years, but a new type of device—eyeglasses that display real-time speech transcription on their lenses—are a game-changing breakthrough. Excerpt – free voice-to-text app on his [David Howorth, a person with multiple causes of hearing loss] phone, Google Live Transcribe & Notification. When someone speaks to him, he can read what they’re saying on the screen and respond as if he’d heard it. He belongs to a weekly lunch group with half a dozen men in their seventies and eighties, and when they get together he puts his phone in the … Read More
“most people don’t simply want to live until 110. They want to extend the amount of time they live free of serious disease, a concept known as health span. That’s why the most sensible approach is to reduce the toll of three major age-related diseases: cancer, heart disease and neurodegenerative disorders, such as Alzheimer’s disease. It may be less flashy, but it’s more attainable than ever. It’s estimated that at least 80 percent of cardiovascular disease cases, 40 percent of cancer cases and 45 percent of Alzheimer’s cases are preventable. Even with a long lag — these diseases can each … Read More
Have American elites—influential journalists, powerful policymakers and other cultural arbiters—learned the lessons of 2020-21? Do they want to? “by 2020, in response to a global pandemic, the dominant part of America’s political and media class had turned the imperative to “follow the science” into an expression of almost religious reverence for the judgment of experts. Many educated and otherwise intelligent Americans, meanwhile, made a single, bespectacled government scientist their idol: “In Fauci We Trust” read their lawn signs and bumper stickers. Their faith was misplaced. Credentialed experts, especially those in the fields of epidemiology and public health, had tied themselves … Read More
The Luddites lost the fight to save their livelihoods. As the threat of artificial intelligence looms, can we do any better? Excerpt – The Luddites rejected the moral and political authority of a system that had abandoned long-held principles of fairness, quality, and mutual obligation. Under feudalism and mercantile capitalism, Britain’s rigid class structure placed the gentry at the top, merchants and professionals (such as doctors, parsons, and lawyers) in the middle, and the vast majority in the “lower orders.” Yet this social hierarchy was accompanied by labor-market regulations—both formal and informal—that provided some measure of reciprocity. Skilled trades were … Read More
“What exactly does it mean to know yourself? For neuroscientists, the answer is straightforward enough: Self-knowledge is the combination of two forms of information, direct appraisals (your own self-beliefs) and reflected appraisals (your perception of how others view you). The first generally employs the parts of the brain associated with a first-person perspective, such as the posterior cingulate; the second with regions associated with emotion and memory, such as the insula, orbitofrontal, and temporal cortex. [..] they [oracles at the Temple of Apollo at Delphi] no doubt meant “Know thyself accurately.” That is a much taller order, requiring a huge … Read More
A plan was set in motion with no idea of how to stop it. “While federal public-health officials made recommendations regarding schools, the actual closures were carried out at the state and local levels, in response to misplaced public fears and aggressive campaigning by teachers’ unions. Randi Weingarten, the high-profile head of the American Federation of Teachers, said in a February 8, 2021, New York Times article that she hoped things would be “as normal as possible” by the following fall. Class-action lawsuits in multiple states had been filed on behalf of children with special needs on the claim that … Read More
“Surgical problems often involve rapid decision-making with limited time for deliberation and require proficiency discussing interventions ranging from elective outpatient procedures to an emergency operation in the setting of life-limiting illness. For patients and families, the concept of surgery may incite strong emotions, with many discussions occurring without a previously established patient-surgeon relationship. [..] Attend to Emotion Receiving bad news such as a new cancer diagnosis or an unexpected postoperative complication often takes patients and families by surprise. Without warning about difficult news, they may fail to process what has happened. To anticipate and attend to their emotions, surgeons can … Read More