Toward Defining Problematic Media Usage Patterns in Adolescents

“In the case of substance abuse, decades of research established a taxonomy that is more nuanced than simply alcohol abuse vs use. The National Institute of Alcohol Abuse and Alcoholism has established different usage patterns that have been studied both for their independent effects on functioning and how each might ultimately lead to the clinical entity of alcohol use disorder (Table). We propose an analogous taxonomy for digital media use that identifies patterns of use, irrespective of content, that could be problematic but, at a minimum, should be flagged as warranting further evaluation and potential remediation. Although in this Viewpoint … Read More

Death and Taxes — Is Alcohol the Solution?

“To help put alcohol taxes in perspective: the federal tax on a pack of cigarettes is now approximately $1, and states and localities can layer on additional taxes. Customers in New York City, for instance, pay a $5.35 state tax and an additional $1.50 city tax for a combined total of $6.85 per pack — far beyond the average state tax of $1.93 nationally. Meanwhile, since the mid-20th century, relative alcohol tax rates have receded by roughly three quarters and have fallen well below those in other high-income countries, in contradistinction to trends in taxation of nicotine products. It has … Read More

Diabetes deaths fall to lowest levels in years, in early CDC figures

“There were 26.4 deaths per 100,000 people from diabetes, according to early death certificate data for the third quarter of 2024 published this month by the CDC’s National Center for Health Statistics.  Death rates from diabetes peaked in 2021, according to CDC figures, at 31.1 deaths per 100,000 people for that year. Diabetes was the eighth leading cause of death in 2021. The CDC says the link between COVID-19 and diabetes may be to blame for that increase.  “Data show an increase in mortality rates for all people during the COVID-19 pandemic, and research shows that people with underlying conditions, … Read More

Routine Surveillance for Cancer Metastases — Does It Help or Harm Patients?

“The theoretical case for routine cancer surveillance is strong. Tumor burden is expected to be lower before signs and symptoms of a recurrence develop; treatment is therefore expected to be more effective when a recurrence is identified by means of routine surveillance. [..] The empirical case for routine cancer surveillance is weak. None of the 12 RCTs assessing imaging-based surveillance that were included in a 2021 systematic review revealed a statistically significant reduction in mortality associated with surveillance. [..] These findings suggest that detection and treatment of asymptomatic cancer recurrences offers no advantage over initiation of treatment only after symptoms … Read More

Cumulative Burden of Digital Health Technologies for Patients With Multimorbidity: A Systemic Review

“We identified all DHTs [digital health technologies] prescribable for a hypothetical patient with 5 chronic conditions (type 2 diabetes, hypertension, chronic obstructive pulmonary disease [COPD], osteoporosis, and osteoarthritis), and assessed the number of DHTs this patient should be prescribed to receive benefits from functions health professionals considered important. We chose to evaluate devices involving hardware and standalone apps together to reflect patients’ perspective, as patients would have to cope with tasks from all DHTs, regardless their nature. [..] We defined DHTs as all software as a medical device (SaMD); implanted, wearable, external, or environmental medical devices driven by software; and … Read More

Avoidable Mortality Across US States and High-Income Countries

“[Introduction] Despite spending more than any country in the world on health care, life expectancy in the US is comparably worse than that of most other high-income countries and declining both in absolute value and relative rank. However, life expectancy across US states varies just as markedly as it does across high-income countries, from 81.8 years in Hawaiʻi to 74.7 years in Mississippi in 2019—a divergence that has been increasing over time. US states vary considerably on policy decisions related to the spending, regulation, and provision of health care; reproductive health; tax policy; social welfare programs; and in relation to … Read More

My Near-Future Dystopia

“Surveillance has always been a part of the human experience, because it’s one of the mechanisms that enables power to be exercised and enforced in society. “No creature is hidden from His sight,” the Bible says, “but all are naked and exposed to the eyes of Him to whom we must give account.” The Quran warns, “God is all-knowing.” Omniscience is not confined to the realm of religious belief. Authoritarian systems share in the idea that, even if you’re hidden behind the walls of your own home, someone might find out that you said the wrong thing or read the … Read More

Uncertainty and proof

“Adam Kucharski, mathematical modeller and Professor of Infectious Disease Epidemiology at the London School of Hygiene & Tropical Medicine in London, UK, was one of the most reliable expert sources for many reporters wrestling with the scientific debates and dilemmas [around COVID-19]. He has now distilled his experience from working on both the pandemic and the epidemiology of other disease outbreaks, such as Zika virus disease and Ebola virus disease, into Proof: The Uncertain Science of Certainty, an exceptionally clear and engaging account of how scientists demonstrate truth and falsity. By showing that the matter often requires us to accept uncertainty … Read More

Modifiable risk factors for stroke, dementia and late-life depression: a systematic review and DALY-weighted risk factors for a composite outcome

“[Abstract] At least 60% of stroke, 40% of dementia and 35% of late-life depression (LLD) are attributable to modifiable risk factors, with great overlap due to shared pathophysiology. [..] Identified risk factors included alcohol (normalised β-coefficient highest category: −34), blood pressure (130), body mass index (70), fasting plasma glucose (94), total cholesterol (22), leisure time cognitive activity (−91), depressive symptoms (57), diet (51), hearing loss (60), kidney function (101), pain (42), physical activity (−56), purpose in life (−50), sleep (76), smoking (91), social engagement (53) and stress (55). [article’s Discussion section] When assessing individual components, hypertension emerged as the factor … Read More

‘This Is Not How We Do Science, Ever’

The Trump administration is manipulating government-sponsored research to get the answers it wants. “Since its first days, the new Trump administration has clearly shown where it thinks scientific attention should not be focused: It has attempted to censor federal scientific data, cut billions in government spending on research, and compromised care for some of the world’s most at-risk populations. Now, as the nation’s leaders have begun to encourage inquiry into specific areas, they are signaling that they’re willing to not just slash and burn research that challenges their political ideology but to replace it with shoddy studies designed to support … Read More