Structural Racism and Long-term Disparities in Youth Exposure to Firearm Violence

“Exposure to firearm violence is associated with lasting consequences for youth and their loved ones. Indirect exposure (eg, witnessing violence) and direct exposure (eg, surviving an assault) can influence mental and physical health outcomes over the life course. In a subset of individuals, exposure is associated with the future enactment of firearm violence, feeding cycles of firearm violence at the community level. [..] At the same time, efforts must directly target the systemic inequities that concentrate firearm violence exposure among Black and Hispanic youth. Racial and ethnic disparities in these outcomes are profound and longstanding. In the study by Lanfear … Read More

Cardiometabolic multimorbidity, lifestyle behaviours, and cognitive function: a multicohort study

An excerpt: Introduction [..] Although an increasing number of studies have focused on the impact of single cardiometabolic diseases on cognitive aging, only a few have considered the associations between their frequent co-occurrence and the loss of cognitive health. Additionally, previous studies of cardiometabolic multimorbidity and cognitive ageing have been limited to only examining individuals from European regions. These countries have a lower prevalence of individuals with cardiometabolic diseases than some countries in Asia, which could potentially lead to different effect estimations regarding the associations between these types of disease and cognitive ageing. [..] Methods This pooled multicohort study utilised data … Read More

Why Americans Feel More Pain

“Tens of millions of Americans are suffering pain. But chronic pain is not just a result of car accidents and workplace injuries but is also linked to troubled childhoods, loneliness, job insecurity and a hundred other pressures on working families. [..] [..] cluster of tightly woven problems that hold back our people and our country: childhood trauma, educational failure, addiction, mental health issues, homelessness, loneliness, family breakdown, unemployment — and, we increasingly recognize, physical pain. “People’s lives are coming apart, and this leads to huge increases in physical pain,” said Angus Deaton, a Nobel Prize winner in economics who with … Read More

Patients and Their Physician’s Perspectives About Oral Anticoagulation in Patients With Atrial Fibrillation Not Receiving an Anticoagulant

“Oral anticoagulation reduces thromboembolic events in patients with nonvalvular atrial fibrillation (AF); however, underuse of anticoagulation is a major issue in treating patients with nonvalvular AF at high stroke risk. Prior data from the American College of Cardiology’s (ACC) Practice Innovation and Clinical Excellence Registry (PINNACLE Registry) has found approximately 40% of patients are not receiving anticoagulants, with little change over time, despite the availability of the nonvitamin K antagonists. Studies examining the reasons for nonuse are sparse. Because underuse may relate to both physician prescribing and patient factors, some studies have looked at physician assessment of the risk of bleeding … Read More

Tired of ‘dead end’ approach, herpes patients mobilize to demand government action

“Herpes care providers and advocates have a variety of concerns, including vaccines and drugs. Although there have been antivirals available for 40 years, they only temporarily suppress the virus. And there are no vaccines; the last major effort to develop one, from GSK, failed in 2010, and there have been few efforts since, though BioNTech and Moderna have recently shown interest in deploying mRNA to that effect. More basically, though, advocates lament that it is difficult for them to even find out if they have the virus. The Centers for Disease Control and Prevention does not recommend that standard STI panels include … Read More

Girls Are Taking Their Pain Out on Themselves

“[Hadley] Freeman, the author of a riveting new memoir, “Good Girls: A Study and Story of Anorexia,” became sick during the 1990s, but over the last few years, the incidence of anorexia, which predominantly affects preteen and teenage girls, seems to have gone up. “During Covid, a lot of published data showed increases in eating disorders both inpatient and some outpatient as well,” Joanna Steinglass, the director of research at the Eating Disorders Research Clinic at Columbia University and the New York State Psychiatric Institute, told me. This increase was true not only in the United States, where Freeman was born, … Read More

e-Cigarette and Cigarette Use Among Youth: Gateway or Common Liability?

“Sun et al studied more than 8000 cigarette-naive youths from [Population Assessment on Tobacco Use and Health (PATH)] waves 3 to 5. They found that youths who had used e-cigarettes at baseline (wave 3) had higher odds of continued cigarette smoking, but the absolute risks of continued smoking at wave 5 were very small and did not significantly differ by baseline e-cigarette use. Moreover, the prevalence of frequent smoking, defined as 20 or more days in the past 30 days, 2 years later (wave 5) was so low (0.2%), the authors could not model this outcome due to its rarity. In … Read More

Association of Cardiovascular Health With Life Expectancy Free of Cardiovascular Disease, Diabetes, Cancer, and Dementia in UK Adults

“The concept of cardiovascular health (CVH) was proposed by the American Heart Association (AHA) in 2010 and is composed of both lifestyle factors and biological metrics. The original algorithm for evaluating CVH was the Life’s Simple 7 (LS7) score. In 2022, the AHA published the new algorithm for evaluating CVH, the Life’s Essential 8 (LE8) score, on the basis of feedback on the LS7 score and new evidence. The LE8 score adopts a new scoring algorithm and incorporates sleep health into CVH.8 Intriguingly, previous studies have shown that having a higher CVH level was not only associated with a lower … Read More

Prevalence of Colorectal Neoplasia 10 or More Years After a Negative Screening Colonoscopy in 120 000 Repeated Screening Colonoscopies

“Screening colonoscopy has been shown to reduce colorectal cancer (CRC) incidence and mortality by enabling detection and removal of precancerous lesions. However, the available evidence about the optimal screening interval is limited. [..] More targeted screening offers would potentially reduce the burden of testing and demand of capacities and costs associated with colonoscopy, thereby also counteracting the frequently reported overuse and underuse of screening examinations in considerable proportions of the population. [..] Anonymized registration of screening colonoscopy findings and the use of the anonymized data for program evaluation by the Central Research Institute of Ambulatory Health Care in Germany is … Read More

Advancing the commercial determinants of health agenda

“By the 1990s, worsening patterns of population health began to raise concerns about their association with these changes in the global political economy. The sharp rise in non-communicable diseases, now accounting for 74% of deaths worldwide, were difficult to explain solely as related to individual behavioural choices. The links between population health outcomes, the strategies and products of corporations, and the political contexts that facilitate such practices began to receive closer scrutiny. Over the next two decades, detailed analyses of an increasingly globalised tobacco industry, enabled by a flood of internal documents into the public domain, were followed by similar … Read More